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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ETS1
All Species:
53.64
Human Site:
Y396
Identified Species:
98.33
UniProt:
P14921
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P14921
NP_005229.1
441
50408
Y396
L
S
R
G
L
R
Y
Y
Y
D
K
N
I
I
H
Chimpanzee
Pan troglodytes
XP_001170891
731
79148
Y686
L
S
R
G
L
R
Y
Y
Y
D
K
N
I
I
H
Rhesus Macaque
Macaca mulatta
XP_001113198
441
50116
Y396
L
S
R
G
L
R
Y
Y
Y
D
K
N
I
I
H
Dog
Lupus familis
XP_546405
441
50378
Y396
L
S
R
G
L
R
Y
Y
Y
D
K
N
I
I
H
Cat
Felis silvestris
Mouse
Mus musculus
P27577
440
50183
Y396
L
S
R
G
L
R
Y
Y
Y
D
K
N
I
I
H
Rat
Rattus norvegicus
P41156
441
50404
Y396
L
S
R
G
L
R
Y
Y
Y
D
K
N
I
I
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508979
473
53725
Y428
L
S
R
G
L
R
Y
Y
Y
D
K
N
I
I
H
Chicken
Gallus gallus
P13474
441
50308
Y396
L
S
R
G
L
R
Y
Y
Y
D
K
N
I
I
H
Frog
Xenopus laevis
P18755
438
50249
Y393
L
S
R
G
L
R
Y
Y
Y
D
K
N
I
I
H
Zebra Danio
Brachydanio rerio
Q9PUQ1
494
55602
Y411
L
S
R
S
L
R
Y
Y
Y
E
K
G
I
M
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P51022
623
66848
Y576
L
S
R
G
L
R
Y
Y
Y
D
K
N
I
I
H
Honey Bee
Apis mellifera
XP_396368
484
53763
Y437
L
S
R
G
L
R
Y
Y
Y
D
K
N
I
I
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_999698
559
62034
Y509
L
S
R
G
L
R
Y
Y
Y
D
K
N
I
I
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
31.4
95.9
99
N.A.
97
98.8
N.A.
52.2
95.9
88.6
23.4
N.A.
28.4
32
N.A.
38.1
Protein Similarity:
100
43.2
96.8
99.5
N.A.
98.4
99.3
N.A.
66.5
97.7
93.8
37.6
N.A.
41
42.5
N.A.
50.8
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
66.6
N.A.
100
100
N.A.
100
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
80
N.A.
100
100
N.A.
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
93
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
93
0
0
0
0
0
0
0
8
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
93
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
100
93
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
100
0
0
0
0
% K
% Leu:
100
0
0
0
100
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
93
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% Q
% Arg:
0
0
100
0
0
100
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
100
0
8
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
100
100
100
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _